How Do You Spell VARIOLATE?

1. Variolate is a verb that refers to the process of intentionally introducing the smallpox virus, known as Variola, into an individual's body as a means of inoculation. This technique was primarily used before the advent of vaccines for smallpox.

   The practice of variolation involves creating a small wound on the skin and then applying material from a smallpox lesion, typically in the form of dried scabs or pus, onto the open wound. The virus would then multiply within the person's body, leading to a mild infection that often resulted in immunity against future, more severe bouts of smallpox.

   Historically, variolation was widely practiced in some regions, especially in parts of Asia and Africa, long before the development of modern vaccines. While variolation could result in a milder form of smallpox, it still carried risks, as some individuals who underwent variolation developed severe symptoms and died due to the infection.

   The introduction of the smallpox vaccine by Edward Jenner in the 18th century marked a significant advancement in the prevention of smallpox and made variolation obsolete. Vaccines provide a safer and more controlled way of stimulating immunity against diseases.

   Overall, "variolate" refers specifically to the act of intentionally infecting an individual with the smallpox virus for the purpose of generating immunity, a practice that has been overshadowed by the development of modern vaccines.

2. 1. To inoculate with smallpox. 2. Pitted or scarred, as if with smallpox.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for VARIOLATE

The word "variolate" is derived from the noun "variola", which refers to smallpox, and the suffix "-ate", which is used to indicate a process or action. The term "variolate" originated in the early 18th century and was used to describe the action of deliberately infecting someone with smallpox as a means of protection against the disease. This practice was an early form of vaccination, using a live (and weakened) strain of smallpox to induce immunity.

Similar spelling words for VARIOLATE

Conjugate verb Variolate

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