SUPPRESSOR CELLS Meaning and
Definition
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Suppressor cells, also known as regulatory T cells or Tregs, are a specific subset of immune cells that play a crucial role in maintaining a balanced immune system. These cells possess the unique ability to suppress or dampen the activity of other immune cells, thereby preventing excessive immune responses that can lead to autoimmune diseases or chronic inflammation.
Suppressor cells have distinct surface markers such as CD4 and FoxP3, which help identify and differentiate them from other immune cells. They are generated in the thymus during T cell development or can be induced from conventional T cells in response to certain signals. Once activated, suppressor cells exert their regulatory function by secreting anti-inflammatory cytokines like interleukin-10 (IL-10) and transforming growth factor-beta (TGF-β), which inhibit the activation and proliferation of other immune cells.
The main role of suppressor cells is to maintain immune homeostasis by preventing immune responses from becoming too intense or prolonged. They act as a self-regulating mechanism that keeps the immune system in check, preventing it from attacking the body's own cells and tissues. Suppressor cells are particularly important in preventing autoimmune diseases, allergies, and excessive inflammation.
Manipulating or modulating the activity of suppressor cells has become an area of interest in medical research. Enhancing their function may have potential therapeutic applications in treating autoimmune disorders, while reducing their activity could be beneficial in boosting immune responses against cancer or infections. Further understanding of suppressor cells and their intricate regulatory mechanisms could offer new insights into immune system modulation and the development of targeted immunotherapies.
Common Misspellings for SUPPRESSOR CELLS
- auppressor cells
- zuppressor cells
- xuppressor cells
- duppressor cells
- euppressor cells
- wuppressor cells
- syppressor cells
- shppressor cells
- sjppressor cells
- sippressor cells
- s8ppressor cells
- s7ppressor cells
- suopressor cells
- sulpressor cells
- su-pressor cells
- su0pressor cells
- suporessor cells
- suplressor cells
- sup-ressor cells
- sup0ressor cells
Etymology of SUPPRESSOR CELLS
The term "Suppressor cells" is derived from the Latin word "supprimere", which means "to press down" or "to suppress". In the context of immunology, suppressor cells refer to a population of immune cells that regulate or suppress the immune response. These cells help maintain immune balance by preventing excessive or prolonged immune activity. The term "suppressor cells" was coined in the 1970s to describe this particular subset of cells and their immunoregulatory function.
Similar spelling word for SUPPRESSOR CELLS
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