NELSON SYNDROME Meaning and
Definition
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Nelson Syndrome is a medical condition that is characterized by the enlargement or growth of a pituitary tumor following the removal of both adrenal glands. This condition primarily affects individuals who have undergone bilateral adrenalectomy, which is the surgical removal of both adrenal glands, typically performed to treat a severe form of a condition called Cushing's disease.
The underlying mechanism of Nelson Syndrome involves the pituitary tumor, known as an adenoma, which stimulates the secretion of adrenocorticotropic hormone (ACTH). This hormone is responsible for the stimulation of the adrenal glands to produce cortisol, a stress hormone. However, in the absence of adrenal glands, the ACTH continues to be released by the pituitary tumor and accumulates in the body.
Symptoms of Nelson Syndrome may include darkening of the skin, weight loss, fatigue, weakness, high blood pressure, and visual disturbances. Due to the excessive ACTH levels, this condition can lead to the enlargement of the pituitary tumor, causing it to invade the surrounding structures in the brain.
Treatment for Nelson Syndrome typically involves surgical intervention to remove or reduce the size of the pituitary tumor. Medications that suppress the ACTH production, such as adrenal-blocking drugs or radiation therapy, may also be used. Regular monitoring and follow-up with healthcare professionals are essential to ensure appropriate management of this condition and to prevent further complications.
Overall, Nelson Syndrome is a rare but significant medical condition that occurs after bilateral adrenalectomy and involves the growth of a pituitary tumor, leading to excessive ACTH production and associated symptoms.
Common Misspellings for NELSON SYNDROME
- belson syndrome
- melson syndrome
- jelson syndrome
- helson syndrome
- nwlson syndrome
- nslson syndrome
- ndlson syndrome
- nrlson syndrome
- n4lson syndrome
- n3lson syndrome
- nekson syndrome
- nepson syndrome
- neoson syndrome
- nelaon syndrome
- nelzon syndrome
- nelxon syndrome
- neldon syndrome
- neleon syndrome
- nelwon syndrome
- nelsin syndrome
Etymology of NELSON SYNDROME
The etymology of the term "Nelson Syndrome" dates back to the 1950s and is closely connected to the renowned British surgeon, Sir Hugh Cairns, who played a significant role in its development.
The name "Nelson" in "Nelson Syndrome" is derived from the distinguished British naval officer, Admiral Lord Nelson. Nelson lost his right eye and right arm during the Battle of Santa Cruz de Tenerife in 1797. Following his injuries, he developed a rather unusual, prominent, and protruding appearance of his remaining left eye, which came to be known as "Nelson's eye".
In the mid-20th century, after the discovery and usage of cortisone and other corticosteroids, the surgical removal of both adrenal glands (bilateral adrenalectomy) became a common treatment for severe Cushing's syndrome – a disorder caused by excess cortisol production.
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