METHIONINE SYNTHETASE Meaning and
Definition
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Methionine Synthetase is an enzyme crucial for the synthesis of the amino acid methionine in living organisms. It is responsible for catalyzing the final step in the synthesis of methionine from homocysteine and methylcobalamin (vitamin B12). This enzyme plays a pivotal role in maintaining adequate levels of methionine, which is an essential amino acid required for the synthesis of proteins and various metabolic processes in the body.
Methionine synthetase is primarily found in liver and kidney tissues, where it functions to convert homocysteine and methylcobalamin into methionine and adenosylcobalamin. Adenosylcobalamin is an active form of vitamin B12, which is required for various enzymatic reactions.
Deficiencies or abnormalities in methionine synthetase can lead to a condition known as methionine synthetase deficiency. This rare genetic disorder is characterized by the inability of the enzyme to function properly, resulting in the accumulation of homocysteine and reduced levels of methionine. Methionine synthetase deficiency can lead to developmental delays, neurological abnormalities, megaloblastic anemia, and other health complications.
In conclusion, methionine synthetase is a crucial enzyme involved in the production of methionine, an essential amino acid required for various biological processes. Deficiencies or abnormalities in this enzyme can have severe consequences on an individual's health and development.
Common Misspellings for METHIONINE SYNTHETASE
- nethionine synthetase
- kethionine synthetase
- jethionine synthetase
- mwthionine synthetase
- msthionine synthetase
- mdthionine synthetase
- mrthionine synthetase
- m4thionine synthetase
- m3thionine synthetase
- merhionine synthetase
- mefhionine synthetase
- meghionine synthetase
- meyhionine synthetase
- me6hionine synthetase
- me5hionine synthetase
- metgionine synthetase
- metbionine synthetase
- metnionine synthetase
- metjionine synthetase
- metuionine synthetase
Etymology of METHIONINE SYNTHETASE
The word "Methionine Synthetase" is derived from two separate components: "Methionine" and "Synthetase".
1. Methionine: The word "Methionine" comes from the Greek word "methy", meaning "wine" or "sweet", along with the suffix "-ine" which is frequently used to denote amino acids. Methionine is an essential amino acid that is commonly found in protein-rich foods.
2. Synthetase: The term "Synthetase" stems from the word "synthesis", which means the process of combining separate elements to form a new compound. In biology, "synthetase" denotes an enzyme responsible for catalyzing the synthesis of specific compounds.
When combined, "Methionine Synthetase" refers to the enzyme that catalyzes the synthesis of methionine, an essential amino acid.
