MALIGNANT HYPERPYREXIA Meaning and
Definition
-
Malignant Hyperpyrexia (MH) is a rare, life-threatening condition characterized by a severe reaction to certain medications used during general anesthesia. It is an inherited disorder that primarily affects individuals who have certain genetic mutations. MH is typically triggered by the administration of certain types of muscle relaxants, such as succinylcholine, and certain inhalational anesthetics, such as halothane.
The condition is characterized by a rapid increase in body temperature, which can rise above 105 degrees Fahrenheit (40.5 degrees Celsius), hence the term "hyperpyrexia." Symptoms of MH can include muscle rigidity, rapid heart rate, increased breathing rate, sweating, and in severe cases, organ failure. Left untreated, MH can be fatal.
The underlying cause of MH is a dysregulation of calcium release in skeletal muscle cells. The genetic mutations associated with MH result in an abnormal response to the medication triggers, causing an uncontrolled release of calcium within the muscle cells. This leads to the severe muscle rigidity and high body temperature seen in individuals with MH.
Early recognition and prompt treatment of MH are crucial to prevent complications and fatalities. Treatment involves stopping the administration of triggering medications, managing the patient's temperature, administering specific medications, and providing supportive care. In some cases, emergency measures like cooling the body or administering dantrolene, a muscle relaxant, may be necessary.
Overall, malignant hyperpyrexia is a serious condition that requires immediate medical intervention and careful monitoring during anesthesia to prevent adverse outcomes.
Common Misspellings for MALIGNANT HYPERPYREXIA
- nalignant hyperpyrexia
- kalignant hyperpyrexia
- jalignant hyperpyrexia
- mzlignant hyperpyrexia
- mslignant hyperpyrexia
- mwlignant hyperpyrexia
- mqlignant hyperpyrexia
- makignant hyperpyrexia
- mapignant hyperpyrexia
- maoignant hyperpyrexia
- malugnant hyperpyrexia
- maljgnant hyperpyrexia
- malkgnant hyperpyrexia
- malognant hyperpyrexia
- mal9gnant hyperpyrexia
- mal8gnant hyperpyrexia
- malifnant hyperpyrexia
- malivnant hyperpyrexia
- malibnant hyperpyrexia
- malihnant hyperpyrexia
Etymology of MALIGNANT HYPERPYREXIA
The word "Malignant Hyperpyrexia" is a medical term that describes a potentially life-threatening condition characterized by a rapid increase in body temperature and severe muscle contractions. Let's break down the etymology of this term:1. Malignant: The term "malignant" comes from the Latin word "malignus", which means "bad" or "evil". In medical terminology, "malignant" is often used to describe diseases or conditions that are severe, dangerous, or have the potential to become life-threatening.2. Hyperpyrexia: The term "hyperpyrexia" is derived from two Greek words. "Hyper" means "excessive" or "above normal", and "pyrexia" means "fever". Therefore, "hyperpyrexia" is used to refer to an extremely high body temperature, typically above 41.5°C (106.7°F).
