LE CELL Meaning and
Definition
-
LE Cell, also known as lupus erythematosus (LE) cell, is a term used in medicine to refer to a unique type of white blood cell that is indicative of systemic lupus erythematosus (SLE). Systemic lupus erythematosus is a chronic autoimmune disease that typically affects various organs and tissues within the body.
The name "LE cell" is derived from the fact that these abnormal cells were first identified by examining cells in the bone marrow under a microscope using a staining technique known as the Lupus erythematosus (LE) test. These cells are phagocytes, a type of white blood cell that engulfs and destroys foreign substances in the body.
LE cells are characterized by the presence of large intracellular inclusion bodies containing engulfed particles, primarily white blood cells or nuclear material from other cells. These inclusion bodies are called "LE bodies" or "LE test cells." The phagocytes containing these inclusion bodies are distinctive due to their appearance, which resembles a "bull's-eye" or a target shape under the microscope.
The presence of LE cells in a patient's blood or bone marrow sample is typically considered diagnostic for systemic lupus erythematosus. However, it is important to note that the LE cell phenomenon is not exclusive to SLE and can occasionally be observed in other autoimmune or inflammatory conditions.
In conclusion, LE cells are abnormal phagocytes that contain distinctive inclusion bodies, called LE bodies or LE test cells, which are characteristic of systemic lupus erythematosus.
Common Misspellings for LE CELL
- ke cell
- pe cell
- oe cell
- lw cell
- ls cell
- ld cell
- lr cell
- l4 cell
- l3 cell
- le xell
- le fell
- le cwll
- le csll
- le cdll
- le crll
- le c4ll
- le c3ll
- le cekl
- le cepl
- le ceol
Etymology of LE CELL
The term "LE cell" is derived from the name of the scientist who first described it, Hargraves LE. LE cells, or Lupus Erythematosus cells, were first identified by Dr. Livingstone E. Hargraves in 1948 during his research on systemic lupus erythematosus, an autoimmune disease. These cells are abnormal white blood cells that have engulfed and are surrounded by nuclear material, forming a characteristic inclusion. The term "LE cell" became widely used to refer to this pathological finding in lupus patients, recognizing the contribution of Dr. Hargraves to its discovery and understanding.
Infographic
Add the infographic to your website:
