KAPPA RECEPTOR Meaning and
Definition
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The kappa receptor refers to a specific type of opioid receptor present in the central nervous system (CNS) that binds to and interacts with the endogenous opioid peptide dynorphin. These receptors are a subclass of the larger family of opioid receptors, which include the mu and delta receptors. The kappa receptor is primarily found in regions related to pain perception and modulation, including the spinal cord and certain areas of the brain, such as the thalamus and cortex.
Activation of the kappa receptor by dynorphin or synthetic kappa agonists can produce analgesic effects, thereby reducing pain sensitivity. However, the activation of this receptor can also induce dysphoria, a state of unease or dissatisfaction. This differentiates the kappa receptor from the mu receptor, which is associated with pain relief and euphoria.
The kappa receptor's activity is involved in various physiological processes, such as the regulation of mood, stress response, and reward systems. It has been implicated in mood disorders, addiction, and the modulation of reward pathways. Researchers are actively studying the kappa receptor and its ligands to better understand its functions, potential therapeutic applications, and the development of drugs targeting this receptor for pain management and psychiatric disorders.
In summary, the kappa receptor is an opioid receptor subtype that plays a crucial role in pain modulation, mood regulation, and stress response in the central nervous system.
Common Misspellings for KAPPA RECEPTOR
- kappa Recepuor
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- kappa Receptmr
- kappa Receptnr
- kappa Recepto2
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- kappa r eceptor
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- kappa recept or
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Etymology of KAPPA RECEPTOR
The word "kappa receptor" is derived from the Greek letter "kappa" (κ), which corresponds to the lowercase letter "k" in the modern English alphabet. In the context of pharmacology and neurobiology, "kappa receptor" refers to a type of opioid receptor called the kappa opioid receptor. The name "kappa" was given to this receptor based on the Greek letter, which is commonly used in scientific nomenclature to designate different types or subtypes of receptors.
