How Do You Spell ICHTHYOSIS FOLLICULARIS?

1. Ichthyosis follicularis is a rare genetic disorder that affects the skin, specifically the hair follicles. It is characterized by the presence of dry, thick, and scaly skin, resembling fish scales. The term "ichthyosis" is derived from the Greek word "ichthys," meaning fish, due to the similarity between the affected skin and fish scales.

   Individuals with ichthyosis follicularis exhibit a range of symptoms, including widespread scaling, especially on the arms, legs, and trunk. The skin may feel rough and may also be prone to cracking and itching. The condition commonly presents at birth or during early childhood, but the severity can vary widely among affected individuals.

   The underlying cause of ichthyosis follicularis is a genetic mutation that affects the expression of certain genes involved in the development and maintenance of skin and hair follicles. Specifically, mutations in the MBTPS2 gene have been implicated in this condition. These mutations disrupt a protein involved in the processing of other proteins necessary for normal skin function.

   Ichthyosis follicularis is typically inherited in an X-linked recessive pattern, meaning that it primarily affects males. However, in rare cases, females can also be affected, usually experiencing milder symptoms. Genetic counseling and testing can help determine the specific inheritance pattern in affected families.

   Although there is no cure for ichthyosis follicularis, treatments focus on managing the symptoms. These may include regular use of moisturizers, keratolytic agents to remove scales, and topical creams or ointments containing urea or lactic acid. In severe cases, additional interventions such as oral retinoids or phototherapy may be considered. Ongoing monitoring by a dermatologist is recommended to tailor treatment to the individual's needs.

2. Keratosis follicularis.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for ICHTHYOSIS FOLLICULARIS

The word "ichthyosis" originates from the Greek word "ichthys" which means "fish". The term "follicularis" is derived from the Latin word "folliculus", meaning "small sac" or "little bag". Therefore, "ichthyosis follicularis" is a term that combines the Greek "ichthyosis" with the Latin "follicularis" to describe a condition characterized by dry, thickened, and scaly skin, resembling fish scales.