HLA DW ANTIGENS Meaning and
Definition
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HLA (human leukocyte antigen) Dw antigens refer to a subset of human leukocyte antigens that are located on genes within the major histocompatibility complex (MHC). The MHC is a region on chromosome 6 in humans and plays a crucial role in the immune system by encoding proteins that are involved in presenting antigens to T cells.
HLA Dw antigens specifically refer to the extended major histocompatibility complex (MHC) class II region, which is composed of a wide range of genes that code for antigen-presenting molecules such as HLA-DR, HLA-DQ, and HLA-DP. These molecules are predominantly found on the surface of antigen-presenting cells (APCs) including B cells, macrophages, and dendritic cells.
The expression of HLA Dw antigens is highly polymorphic, meaning that there are multiple variant forms of these antigens within the human population. This polymorphism is what enables the immune system to recognize and respond to a wide range of foreign substances, or antigens. By presenting antigens on HLA Dw antigens to T cells, an immune response can be triggered, leading to the production of antibodies, activation of cytotoxic T cells, and other defense mechanisms within the body.
The polymorphic nature of HLA Dw antigens is also a key factor in organ transplantation. A close match in HLA compatibility between the donor and recipient is crucial to minimize the risk of organ rejection by the recipient's immune system. Determining the HLA Dw antigen profile of individuals is therefore an important aspect of tissue typing for transplantation purposes.
Common Misspellings for HLA DW ANTIGENS
- hla aq antigens
- hla fq antigens
- gla dw antigens
- bla dw antigens
- nla dw antigens
- jla dw antigens
- ula dw antigens
- yla dw antigens
- hka dw antigens
- hpa dw antigens
- hoa dw antigens
- hlz dw antigens
- hls dw antigens
- hlw dw antigens
- hlq dw antigens
- hla sw antigens
- hla xw antigens
- hla cw antigens
- hla fw antigens
- hla rw antigens
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