How Do You Spell GRAFFI CHLOROLEUKEMIC STRAIN?

1. Graffi Chloroleukemic Strain is a term used in medical research to describe a specific type of laboratory-induced tumor model in mice. It refers to a strain of mice that develops a form of leukemia known as chloroleukemia, which has been artificially induced by the Graffi virus.

   The term "Graffi" refers to the specific virus used to induce the leukemia in these mice. The Graffi virus belongs to the family Retroviridae and is commonly used in experimental studies to induce various types of tumors, particularly leukemias and lymphomas.

   "Chloroleukemia" describes a sub-type of leukemia characterized by the abnormal proliferation of immature white blood cells called blast cells that possess green-colored cytoplasm due to the presence of chloroplasts. These chloroplasts are not typically found in mammalian cells and are often a result of genetic modifications made to the mice to enable them to produce green cytoplasmic pigments. This allows researchers to easily identify and study these leukemia cells under a microscope.

   The "Strain" aspect of the term refers to the specific genetic and phenotypic characteristics of the mice that have been selectively bred to ensure consistency and reproducibility in experimental studies.

   Overall, the term "Graffi Chloroleukemic Strain" represents a specific mouse model that has been developed for the purpose of studying and investigating the mechanisms, treatment options, and potential therapies for chloroleukemia.

Common Misspellings for GRAFFI CHLOROLEUKEMIC STRAIN