COAGULATION FACTORS Meaning and
Definition
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Coagulation factors are a group of proteins and enzymes in the blood that play a crucial role in the process of blood clotting, also known as coagulation. When a blood vessel is damaged, the coagulation factors work together in a cascade-like sequence to form a stable blood clot, preventing excessive bleeding.
There are multiple coagulation factors identified, each labeled with a Roman numeral. The major coagulation factors include Factor I (Fibrinogen), Factor II (Prothrombin), Factor III (Tissue Factor), Factor IV (Calcium), Factor V (Proaccelerin), Factor VII (Proconvertin), Factor VIII (Antihemophilic Factor A), Factor IX (Antihemophilic Factor B or Christmas Factor), Factor X (Stuart-Prower Factor), Factor XI (Antihemophilic Factor C), Factor XII (Hageman Factor), and Factor XIII (Fibrin-Stabilizing Factor). These coagulation factors are synthesized in the liver, with their production assisted by Vitamin K.
Deficiencies or abnormalities in coagulation factors can result in bleeding disorders or excessive clotting disorders, respectively. Conditions such as hemophilia and von Willebrand disease are examples of genetic disorders that affect the production or function of specific coagulation factors. In certain medical scenarios, such as surgery or trauma, the administration of specific coagulation factors or blood clotting medications may be necessary to control bleeding or prevent complications.
Understanding the role and functions of coagulation factors is essential in diagnosing and managing bleeding disorders, as well as maintaining the delicate balance between clotting and bleeding in various medical situations.
Common Misspellings for COAGULATION FACTORS
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Etymology of COAGULATION FACTORS
The term "coagulation factors" originates from the field of hematology and refers to a group of proteins involved in the process of blood clotting or coagulation. The word "coagulation" comes from the Latin word "coagulare", meaning "to curdle or clot". "Factors" simply refers to the proteins that play a role in this process. Therefore, "coagulation factors" can be understood as the proteins that aid in the clotting of blood.
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