CARBAMYL PHOSPHATE Meaning and
Definition
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Carbamyl Phosphate is a chemical compound that plays a crucial role in various biochemical processes within living organisms. It is an intermediate molecule involved in the urea cycle, a metabolic pathway in the liver that detoxifies ammonia, a toxic byproduct of protein metabolism, by converting it into less harmful urea.
Chemically, carbamyl phosphate is an organic phosphate compound with the formula (NH2CO)2PO4. It is synthesized in the liver mitochondria through the condensation of bicarbonate (HCO3-), ammonia (NH3), and adenosine triphosphate (ATP) by the enzyme carbamyl phosphate synthetase. This reaction is the first and rate-limiting step of the urea cycle.
Functionally, carbamyl phosphate acts as an activator and donor of the carbamyl group, which is essential for the subsequent steps of the urea cycle. It is further converted into citrulline through the action of the enzyme ornithine transcarbamylase, leading to the incorporation of additional amino groups and the eventual formation of urea.
Outside the urea cycle, carbamyl phosphate also participates in the synthesis of other essential biomolecules such as arginine, pyrimidines, and the amino acid histidine. Furthermore, it has been found to have regulatory effects on various metabolic pathways and enzyme activities, making it a crucial molecule in maintaining nitrogen balance and overall metabolic homeostasis.
Common Misspellings for CARBAMYL PHOSPHATE
- xarbamyl phosphate
- varbamyl phosphate
- farbamyl phosphate
- darbamyl phosphate
- czrbamyl phosphate
- csrbamyl phosphate
- cwrbamyl phosphate
- cqrbamyl phosphate
- caebamyl phosphate
- cadbamyl phosphate
- cafbamyl phosphate
- catbamyl phosphate
- ca5bamyl phosphate
- ca4bamyl phosphate
- carvamyl phosphate
- carnamyl phosphate
- carhamyl phosphate
- cargamyl phosphate
- carbzmyl phosphate
- carbsmyl phosphate
Etymology of CARBAMYL PHOSPHATE
The word "Carbamyl Phosphate" is a scientific term composed of two parts: "carbamyl" and "phosphate".
The term "carbamyl" is derived from the word "carbamide", which is an alternative name for urea. "Carbamide" comes from the French term "urée", which was coined by the French chemist Jean-Antoine Chaptal in 1806. Chaptal derived the term from the Greek word "ouron", meaning "urine", as urea was first isolated from urine.
The term "phosphate" originates from the Greek word "phosphoros", which means "light-bringer" or "light-bearer". The element phosphorus was originally named by the alchemist Hennig Brand in the 17th century, who derived it from the Greek word due to its ability to emit a faint glow.
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