BIOZZI MICE Meaning and
Definition
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Biozzi mice are a type of laboratory mice that are commonly used in biomedical research due to their special genetic features and susceptibility to certain diseases. These mice were initially developed by Giuseppe Biozzi and his colleagues in the mid-20th century by selective breeding of two strains of Swiss albino mice. The resulting Biozzi mice strains, such as the Biozzi High and Low strains, have distinctive genetic traits that make them valuable models for studying various autoimmune diseases and other immunological disorders.
The main characteristic of Biozzi mice is their heightened susceptibility to induced autoimmune diseases, which makes them ideal for investigating the underlying mechanisms and potential treatments for such conditions. These mice exhibit symptoms similar to those observed in human autoimmune diseases, making them valuable tools for studying the pathogenesis, progression, and treatment of disorders like systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis.
The susceptibility of Biozzi mice to these diseases is thought to be influenced by complex interactions between multiple genes, including those related to the immune system and regulation of inflammatory responses. Researchers can utilize these mice to explore the genetic and environmental factors that contribute to the development of autoimmune diseases, as well as to test potential therapeutic interventions.
In summary, Biozzi mice are a specific breed of laboratory mice with distinctive genetic traits that make them highly valuable for studying autoimmune diseases and related immunological disorders. Their susceptibility to induced autoimmune conditions allows researchers to gain valuable insights into disease mechanisms, treatment options, and potential interventions.
Common Misspellings for BIOZZI MICE
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