ALA DEHYDRASE Meaning and
Definition
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ALA dehydrase, also known as delta-aminolevulinic acid (ALA) dehydratase, is a critical enzyme involved in the synthesis of heme, a vital component of hemoglobin and other crucial proteins in the body. Heme plays a vital role in the transportation of oxygen throughout the body and in various metabolic processes. It is primarily found in the liver, bone marrow, and red blood cells.
ALA dehydrase catalyzes the second step of the heme biosynthesis pathway, which involves the conversion of ALA to porphobilinogen. This conversion occurs in a series of enzymatic reactions, and ALA dehydrase specifically facilitates the removal of water molecules from two molecules of ALA, resulting in the formation of porphobilinogen.
Inhibition or deficiency of ALA dehydrase can have severe consequences on heme synthesis, leading to a condition known as lead poisoning. This is because lead can bind to and inhibit the activity of ALA dehydrase, disrupting the production of heme. The resulting heme deficiency can lead to impaired oxygen transport, reduced red blood cell production, and other symptoms characteristic of lead poisoning, such as anemia, neurological damage, and gastrointestinal issues.
Measuring the activity of ALA dehydrase through laboratory tests can aid in the diagnosis and monitoring of lead poisoning. Treatment for lead poisoning may involve removing the source of lead exposure, chelation therapy to remove excess lead from the body, and addressing any resultant medical complications.
Common Misspellings for ALA DEHYDRASE
- zla dehydrase
- sla dehydrase
- wla dehydrase
- qla dehydrase
- aka dehydrase
- apa dehydrase
- aoa dehydrase
- alz dehydrase
- als dehydrase
- alw dehydrase
- alq dehydrase
- ala sehydrase
- ala xehydrase
- ala cehydrase
- ala fehydrase
- ala rehydrase
- ala eehydrase
- ala dwhydrase
- ala dshydrase
- ala ddhydrase
Etymology of ALA DEHYDRASE
The term "ALA Dehydrase" is not commonly used in scientific literature or medical terminology. However, it seems to suggest a combination of two different concepts: "ALA" and "Dehydrase".
"ALA" stands for "Aminolevulinic Acid", an organic compound involved in the synthesis of heme, a crucial component of hemoglobin. The etymology of "Aminolevulinic Acid" originates from combining "amino", meaning containing nitrogen, and "levulinic acid", which is a type of organic acid.
"Dehydrase" refers to an enzyme that catalyzes the removal of water from a substance during a chemical reaction, such as dehydrating or removing water from a molecule. The suffix "-ase" in biochemistry is commonly used to name enzymes.
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